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	<title>Comments on: Eye on DNA Headlines for 6 September 2007</title>
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	<link>http://www.eyeondna.com/2007/09/06/eye-on-dna-headlines-for-6-september-2007/</link>
	<description>How will it change your life?</description>
	<pubDate>Tue, 07 Oct 2008 19:35:05 +0000</pubDate>
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		<title>By: Hsien</title>
		<link>http://www.eyeondna.com/2007/09/06/eye-on-dna-headlines-for-6-september-2007/#comment-7301</link>
		<dc:creator>Hsien</dc:creator>
		<pubDate>Fri, 07 Sep 2007 12:34:10 +0000</pubDate>
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		<description>Bryan's a smart guy but I think he's in some sort of denial about his genealogy. 

What are you hiding, Bryan??</description>
		<content:encoded><![CDATA[<p>Bryan&#8217;s a smart guy but I think he&#8217;s in some sort of denial about his genealogy. </p>
<p>What are you hiding, Bryan??</p>
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		<title>By: Hsien</title>
		<link>http://www.eyeondna.com/2007/09/06/eye-on-dna-headlines-for-6-september-2007/#comment-7300</link>
		<dc:creator>Hsien</dc:creator>
		<pubDate>Fri, 07 Sep 2007 12:33:06 +0000</pubDate>
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		<description>Of course it wouldn't surprise you, Dr. Gene Sherpa Steve. ;)</description>
		<content:encoded><![CDATA[<p>Of course it wouldn&#8217;t surprise you, Dr. Gene Sherpa Steve. <img src='http://www.eyeondna.com/wp-includes/images/smilies/icon_wink.gif' alt=';)' class='wp-smiley' /></p>
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		<title>By: StevenMurphy MD</title>
		<link>http://www.eyeondna.com/2007/09/06/eye-on-dna-headlines-for-6-september-2007/#comment-7202</link>
		<dc:creator>StevenMurphy MD</dc:creator>
		<pubDate>Fri, 07 Sep 2007 01:37:00 +0000</pubDate>
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		<description>The STAT4 finding doesn't surprise me.....There is actually a condition called rhupus which has findings of both rheumatoid and lupus.
-Steve
www.thegenesherpa.blogspot.com</description>
		<content:encoded><![CDATA[<p>The STAT4 finding doesn&#8217;t surprise me&#8230;..There is actually a condition called rhupus which has findings of both rheumatoid and lupus.<br />
-Steve<br />
<a href="http://www.thegenesherpa.blogspot.com" >http://www.thegenesherpa.blogspot.com</a></p>
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		<title>By: The Genetic Genealogist</title>
		<link>http://www.eyeondna.com/2007/09/06/eye-on-dna-headlines-for-6-september-2007/#comment-7129</link>
		<dc:creator>The Genetic Genealogist</dc:creator>
		<pubDate>Thu, 06 Sep 2007 18:52:19 +0000</pubDate>
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		<description>Oh boy!  Thanks for the link to Mr. Appleyard!  I can't help myself, I have to write a quick response.  I agree with Mr. Appleyard about the dilution of genes and genealogy over time.  That's part of the reason that autosomal genetic genealogy is so challenging.

However, Mr. Appleyard is not taking into account the Y-DNA and mtDNA tests.  Generally speaking, Y-DNA &lt;strong&gt;IS&lt;/strong&gt; passed down directly from father to son without dilution.  And mtDNA &lt;strong&gt;IS&lt;/strong&gt; passed down from mother to child without dilution.  Thus, these tests DO give us a direct picture of our direct paternal and maternal lines.  

Now, the caveat Mr. Appleyard should bring up in response to that assertion is that at 10 generations, our Y-DNA and mtDNA only describe a portion of 2 out of (potentially) 1024 individuals.  This is a completely valid point, and one of the limitations of genetic genealogy.  As I always say, 2 out of 1024 ain't bad!</description>
		<content:encoded><![CDATA[<p>Oh boy!  Thanks for the link to Mr. Appleyard!  I can&#8217;t help myself, I have to write a quick response.  I agree with Mr. Appleyard about the dilution of genes and genealogy over time.  That&#8217;s part of the reason that autosomal genetic genealogy is so challenging.</p>
<p>However, Mr. Appleyard is not taking into account the Y-DNA and mtDNA tests.  Generally speaking, Y-DNA <strong>IS</strong> passed down directly from father to son without dilution.  And mtDNA <strong>IS</strong> passed down from mother to child without dilution.  Thus, these tests DO give us a direct picture of our direct paternal and maternal lines.  </p>
<p>Now, the caveat Mr. Appleyard should bring up in response to that assertion is that at 10 generations, our Y-DNA and mtDNA only describe a portion of 2 out of (potentially) 1024 individuals.  This is a completely valid point, and one of the limitations of genetic genealogy.  As I always say, 2 out of 1024 ain&#8217;t bad!</p>
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