2007 Nobel Prize in Medicine Goes To Mice Geneticists
by Dr. Hsien-Hsien Lei
Posted October 8, 2007 in DNA Lab Talk, Genetic Engineering
Congratulations to Mario R. Capecchi, Oliver Smithies, and Sir Martin J Evans who won the 2007 Nobel Prize in medicine today! The announcement was made just minutes ago and their pictures aren’t even up on the Nobel Prize site yet.
The 2007 Nobel Prize in Physiology or Medicine goes to Mario R. Capecchi, Martin J. Evans, and Oliver Smithies for their discoveries of principles for introducing specific gene modifications in mice by the use of embryonic stem cells.
The three Nobel Laureates pioneered gene targeting in mice which can be used to inactivate single genes to create “knockout” mice. Over ten thousand mouse genes have been knocked out and studied thus far and over five hundred different mouse models of human disorders have been created.
More about the fascinating gene-targeting experiments in the Nobel Prize Press Release.
Photo: Knockout mice from Wellcome Images under Creative Commons
Tags: genetics, genes, dna, mice, knockout mice, gene targeting, mario capecchi, oliver smithies, sir martin evans, nobel prize, medicine, science
Related Posts:
Image of Transgenic Mouse Embryo Wins Nikon Small World Photomicrography Competition...
Geneticist Barbara McClintock in The Daring Book for Girls...
DNA Video: Archon X PRIZE for Genomics...
DNA Technology Makes Spiked List of Greatest Innovations...
DNA Quote: Sir William Bragg on Science...
Books About DNA: Coming to Life by Christiane Nusslein-Volhard...
Eye on DNA Headlines for 15 April 2008...
Please note that comments left using the form below will be publicly displayed. If you'd like to correspond with me privately, please email me at hsien@eyeondna.com.
If your comment doesn't show up immediately, it's probably in moderation. I will approve it as soon as I can! Thanks for your patience.
7 Comments »
Search Eye on DNA
- Michael Jackson May Have Had Genetic Lung Disease Alpha-1 Antitrypsin Deficiency
- Twin DNA Foil Investigators Again
- Regulatin’ Genes Video
- Yay or Nay for Genetic Testing?
- American Clinical Laboratory Association Tips for Consumers of Genetic Tests
- Navigenics Introduces Physician Portal and Annual Insight Service
- Eye on DNA Interview: Dr. Tzung-Fu Hsieh of RedTracer DNA Test for the Red Hair Gene, MC1R
- Books About DNA: The Crime of Reason by Robert B. Laughlin
- What does DNA mean to you?
- Genetically Modified Organisms Bring in the Cash
MOST POPULAR
- DNA Toys: Ben 10 and Digimon Digivice
- 100 Facts About DNA
- Genetically Modified Organisms Bring in the Cash
- What does DNA mean to you?
- Parenting Children Using Genetic Tests
- Books About DNA: The Crime of Reason by Robert B. Laughlin
- Eye on DNA Interview: Dr. Tzung-Fu Hsieh of RedTracer DNA Test for the Red Hair Gene, MC1R
- Navigenics Introduces Physician Portal and Annual Insight Service
- American Clinical Laboratory Association Tips for Consumers of Genetic Tests
- Salaries for Jobs in Genetics
- Michael Jackson May Have Had Genetic Lung Disease Alpha-1 Antitrypsin Deficiency
07/02/2009 01:44 pm
2 Comments - Is the Pink or Blue early baby gender DNA test accurate?
05/27/2009 08:25 am
78 Comments - New Line Genetics and SellMyDNA.com Offer $5,000 for Your DNA
05/06/2009 03:56 am
33 Comments - Boston Celebrities Donate DNA for Genographic Project
05/05/2009 08:07 am
6 Comments - Twin DNA Foil Investigators Again
05/02/2009 11:32 pm
3 Comments - Business of DNA
- DNA @ Google Answers
- DNA and Disease
- DNA and Genealogy
- DNA and the Law
- DNA Around the World
- DNA Fun
- DNA in General
- DNA Inventions and Gadgets
- DNA Lab Talk
- DNA Podcasts and Videos
- DNA Quotes and Excerpts
- DNA Testing
- Gene Therapy
- Genetic Engineering
- Genetically Modified Foods and Organisms
- Jobs Involving DNA
- Personalities with DNA
- Polls About DNA
RECENT POSTS
RECENT COMMENTS
CATEGORIES
ARCHIVE
- June 2009
- March 2009
- February 2009
- January 2009
- December 2008
- November 2008
- October 2008
- September 2008
- August 2008
- July 2008
- June 2008
- May 2008
- April 2008
- March 2008
- February 2008
- January 2008
- December 2007
- November 2007
- October 2007
- September 2007
- August 2007
- July 2007
- June 2007
- May 2007
- April 2007
RANDOMIZED BLOGROLL
- Mary Meets Dolly
- miggawki
- Philosophy of Genetics
- Gene Expression
- World Science
- Evolution…Not “Just a Theory” Anymore
- Genomicron
- Christina Loves
- Sandwalk
- The Daily Transcript
| We comply with the HONcode standard for trustworthy health information: verify here. |
I’m surprised this type of work is Nobel worthy! Congrats to them! What matters most is that they have developed technology that has lead to mouse models of human diseases. Knocking out genes is nice, but understanding the role that the gene has in the development of the disease more important. Without understanding the function of the gene, we won’t fully understand the protein function.
Hi NA, I am certainly not one to judge what is or is not Nobel worthy. However, figuring out that homologous recombination can be used to introduce new genetic material into a mammalian genome and the use of embryonic stem cells to introduce genes into the germ line are not small accomplishments!
[...] Competition by Dr. Hsien-Hsien Lei Posted October 8, 2007 in DNA Fun Following up on today’s announcement of the Nobel Prize for medicine , here’s the 2007 Nikon Small World Photomicrography Competition 1st place winner: Double [...]
[...] What is the Importance of New Discoveries? The three Nobel Laureates pioneered gene targeting in mice which can be used to inactivate single genes to create “knockout†mice. Over ten thousand mouse genes have been knocked out and studied thus far and over five hundred different mouse models of human disorders have been created. quoted from eyeondna.com [...]
[...] 2007 Nobel Prize in Medicine Goes To Mice Geneticists (Eye on DNA) [...]
I am glad to see that a bit of important basic research won the prize. Knockout mice are so important for, well, nearly everything. Did they have anything to do with knock in technology as well?
Just wanted to share some thoughts I saw elsewhere on the matter:
http://pacificresearch.org/blog/id.191/blog_detail.asp