by Dr. Hsien-Hsien Lei
Posted October 8, 2007 in DNA Lab Talk, Genetic Engineering
Congratulations to Mario R. Capecchi, Oliver Smithies, and Sir Martin J Evans who won the 2007 Nobel Prize in medicine today! The announcement was made just minutes ago and their pictures aren’t even up on the Nobel Prize site yet.
The 2007 Nobel Prize in Physiology or Medicine goes to Mario R. Capecchi, Martin J. Evans, and Oliver Smithies for their discoveries of principles for introducing specific gene modifications in mice by the use of embryonic stem cells.
The three Nobel Laureates pioneered gene targeting in mice which can be used to inactivate single genes to create “knockout” mice. Over ten thousand mouse genes have been knocked out and studied thus far and over five hundred different mouse models of human disorders have been created.
More about the fascinating gene-targeting experiments in the Nobel Prize Press Release.
Photo: Knockout mice from Wellcome Images under Creative Commons
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